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Triple Lipid Restore 2:4:2 Anti-aging cream

Triple Lipid Restore 2:4:2 is rated 4.7 out of 5 by 510.
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A patented anti-aging cream to refill cellular lipids and nourish dry skin. U.S. Patent No. 10,137,073.

skin types

Dry
Normal
Oily
Combination
Sensitive

skin condition

Dehydrated
Aging

$128.00

Availability:

In Stock

Product Details

Triple Lipid Restore 2:4:2 is an anti-aging cream that contains the optimal and patented lipid ratio of 2% pure ceramides 1 and 3, 4% natural cholesterol, and 2% fatty acids, which is proven to nourish skin and correct signs of aging. This unique lipid correction cream contains the first 2:4:2 cholesterol-dominant ratio to help restore skin's external barrier and support natural self-repair, while potently nourishing aging skin for improvement in the visible appearance of skin smoothness, laxity, pores, and overall radiance.

  • Restores essential skin lipids: ceramides, natural cholesterol, and fatty acids
  • Improves the look of skin fullness, texture, and pore appearance
  • Improves the appearance of skin evenness and overall radiance
  • Unique lipid stabilization system in a lightweight and fast-absorbing texture
  • Shortens the adjustment period to retinoids up to 1 week while reducing dryness (see Science & Proof below)
  • Paraben-, and dye-free
  • Ideal for aging, normal, and dry skin types


Learn more about the science behind Triple Lipid Restore 2:4:2

How To Use

Apply a small amount between fingertips, warm and melt the cream in circular motions. Apply once or twice daily to face, neck, and chest. If using in the morning, apply after a SkinCeuticals vitamin C antioxidant serum and before a SkinCeuticals sunscreen. If using with a retinol at night, apply after retinol application.

  • Visible Results

  • before
    after

    CLINICAL STUDY

    In an 8-week study, Triple Lipid Restore 2:4:2 significantly improved the appearance of key visible signs of accelerated aging:1

    • 66% improvement in smoothness
    • 35% improvement in laxity
    • 20% improvement in evenness
    • 26% improvement in radiance
    • 44% improvement in pore appearance

    In a lipidomic study, use of this cream resulted in a 57% increase in ceramides, 50% increase in cholesterol, and 12% increase in fatty acids in the form of triglycerides.2

    See Protocol

    1Protocol: Average results shown. A dermatologist-controlled 8-week clinical study on 55 subjects with twice daily application of Triple Lipid Restore 2:4:2. Subjects also used SkinCeuticals Gentle Cleanser and Ultimate UV Defense SPF 30. Inclusion Criteria: Females ages 55-75 with moderate fi ne lines/wrinkles, uneven skin tone, skin dullness, skin roughness, lack of skin tone clarity, and lack of skin firmness.

    2Protocol: Average results shown. Lipidomics analysis (N=28 females aged 55-75). Statistically significant increase in lipids determined by spectrometric analysis of tape strips collected at baseline and after 8 weeks of twice daily application of Triple Lipid Restore 2:4:2..

  • Science & Proof


  • Science

    Aging skin is increasingly susceptible to lipid depletion: the loss of natural compounds in skin’s surface, present in the predominant form of ceramides, natural cholesterol, and fatty acids. This lipid loss occurs with age and compromises skin’s natural protective barrier, resulting in visible signs of accelerated aging, as skin loses its ability to effectively self-repair. As a result, visible signs of aging may appear more pronounced, in the form of skin roughness, uncomfortable tightness, dullness, and loss of facial fullness.

    Triple Lipid Restore 2:4:2 is the first anti-aging cream to directly address age-related lipid loss with a 2:4:2 cholesterol-dominant ratio, this formulation contains maximized concentration of pure lipids easily utilized by skin.

    Retinoids are known as one of the best anti-aging skin care treatments, but the adjustment period can cause redness, peeling, and flaky skin. Triple Lipid Restore 2:4:2 is now shown to shorten the adjustment period to retinoids up to 1 week while reducing dryness.*

    See Protocol

    *Protocol: 4-week study, on 17 female subjects, ages 38 to 64, who were retinoid averse (self-reported). Subjects applied topical 0.025% tretinoin to their entire face every other evening, or every evening, depending on tolerability. Triple Lipid Restore 2:4:2 and a comparative competitor product were applied to the face twice a day after retinoid application in a split-face, randomized manner.

Key Ingredients

  • 2% Pure Ceramides 1 & 3
  • 4% Natural Cholesterol
  • 2% Fatty Acids
  • Essential oil blend

Part of a larger family of ceramides, and proven to synergistically increase hydration and optimal barrier function

Learn more about Pure Ceramides 1 & 3

See all ingredients

aqua/water/eau, dimethicone, hydrogenated polyisobutene, glycerin, cholesterol, c12-15 alkyl benzoate, ceramide 3, helianthus annuus seed oil unsaponifiables/sunflower seed oil unsaponifiables, bis-peg-18 methyl ether dimethyl silane, sodium polyacrylate, peg-10 dimethicone, nylon-12, lauryl peg-9 polydimethylsiloxyethyl dimethicone, dimethicone/peg-10/15 crosspolymer, phenoxyethanol, disteardimonium hectorite, hydroxyethylpiperazine ethane sulfonic acid, ammonium polyacryloyldimethyl taurate, chlorphenesin, caprylyl glycol, peg/ppg-18/18 dimethicone, propylene carbonate, disodium edta, acrylonitrile/methyl methacrylate/vinylidene chloride copolymer, adenosine, dipropylene glycol, lavandula angustifolia oil/lavender oil, rosmarinus officinalis leaf oil/rosemary leaf oil, t-butyl alcohol, mentha piperita oil/peppermint oil, sodium citrate, linalool, isobutane, ceramide eop, bht, tocopherol, limonene, d182888/1

Physician Insight

Physician image

I think Triple Lipid Restore 2:4:2 is the best corrective cream on the market. I recommend it to all of my patients after surgery to help with the natural dryness that occurs post-op. They love it!

Dr. Michael E. Kelly – Miami Plastic Surgery

Learn about Dr. Michael E. Kelly

Complete Your Regimen

Reviews

Rated 5 out of 5 by from Love this product I love everything about this product, especially how it makes my skin feel, and look. I've been using it along with the CE Ferulic serum for over a year, and cannot believe the change in my skin's texture and appearance. No fine lines, and dark spots are starting to diminish. Win win for me.
Date published: 2020-08-01
Rated 5 out of 5 by from Great Cream! I received a sample of this cream and instantly loved it. It feels luxurious to put on and my skin feels so smooth afterwards.
Date published: 2020-07-28
Rated 5 out of 5 by from Skinceuticals Triple Lipid Restore I received a free sample of Skinceuticals Triple Lipid Restore. I love how my skin felt soft and was moisturized from Skinceuticals Triple Lipid Restore. My skin looks smoother and younger from this wonderful product.
Date published: 2020-07-23
Rated 4 out of 5 by from Good product Have been using this around 1 month. It's very hydrating and my skin’s appearance looks good.
Date published: 2020-07-23
Rated 5 out of 5 by from It Really Works!!! I was looking for something with more than just a moisturizer. I love SkinCeuticals and bought the Triple Lipid Restore 2: 4 :6 . It's not like other moisturizers. I've already bought another jar of the Triple Lipid Restore 2:4:6 even thought I have more than 1/2 left. I don't want to run out of this cream with lipids, peptides, etc that makes my skin look more youthful.
Date published: 2020-07-22
Rated 5 out of 5 by from Wouldn’t want to do without I have been using Triple Lipid Restore for about a year. I believe it is keeping my skin, along with some other Skinceutical products, looking as good as possible.
Date published: 2020-07-06
Rated 4 out of 5 by from lightweight I tried a sample tube and I was able to use it twice. Overall it's light weight and creamy. Yet I don't feel and big difference in my skin. I like that it didn't cause ny skin irritation or redness. It seems to absorb well into the skin as well. It does leave a hydrating layer on your skin.
Date published: 2020-06-26
Rated 5 out of 5 by from Hydrating Have been using this for about 3 months. Very hydrating and has improved my skin’s appearance overall. I have really noticed a major improvement in the mouth & chin areas.
Date published: 2020-05-30
  • y_2020, m_8, d_18, h_24
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.10
  • cp_1, bvpage1
  • co_hasreviews, tv_4, tr_506
  • loc_en_US, sid_3606000434967, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_skinceuticals-us
  • bvseo_sdk, dw_cartridge, 17.1.0, p_sdk_3.2.0
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  • reviews, product